NanoGenizer-Quad High Pressure Homogenizer

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Description
How to Use
FAQs and Tips
How to Order

Description:

Laboratory Quad-Pump up to 30,000 psi with concept testing of parallel and series flow direction.

Application:

Nanodispersions, nanoemulsions and nanotube
Cell disruption
Micro/nanoencapsulation in polymers, liposomes and oils
Solid dispersion and suspension, deagglomeration

Performance:

Energy efficient, 1/2 energy loss of the most homogenizers
Small (integrated design delivers the light weight and small dimensions)
Smart (programming control systems confer diligent functions: auto stop with time/volume)
Silent (noiseless performance)
Strong (6-27L/hr)
CE compliant and RoHs compliant

Specification
Catalog No.	NanoGenizer-Quad
Flow Rate	6-27L/hr
Min. Sample	5mL
Max. Pressure	30,000psi
Dimensions(cm)	92 × 69 × 40
Weight	117 kg (258 lbs)
Max. Temp.	80ºC (176ºF)
Power	220V
Cleaning	Flush to clean
Application	Nano emulsion, fat emulsion, liposome, cell disruption, nano dispersion, deagglomeration
Features	Digital display of pressure or pressure gauge

Standard Features
Parts	Y-type diamond interaction chamber with cooling option
Control System	High pressure programming control systems: touch screen, speed control, auto stop control by volume, time, pressure or temperature, display of flow rate and time, overload protection
Pressure Gauge	Digital display on the touch screen
Inlet Type	Tri-clamp
Outlet Type	Tri-clamp
Inlet Reservoir	500mL S/S cylinder
Outlet Reservoir	Plastic hose
Product Material	316L stainless steel, tungsten carbide, viton, teflon
Material Standard	Sanitary grade, FDA, GMP
Warranty	1 year against any manufacturing defects

Option Features
Parts	High pressure extruders, homogenizing valves, heat exchanger
Control System	Mechanical control: speed, start, stop controls
Detector	Pressure gauge, pressure transducer up to 8 optional, temperature transducer up to 8 optional
Outlet Type	Tri-clamp or luer
Inlet Reservoir	10mL, 20mL, 50mL, 100mL, 200mL syringe, S/S cylinder, jacketed glass cylinder or online
Outlet Reservoir	10mL, 20mL, 50mL, 100mL, 200mL, syringe, S/S cylinder, jacketed glass cylinder or online
Cylinder	Titanium high pressure cylinder (resistant to strong acid and base)

Varieties of Inlet and Outlet for NanoGenizer-Quad

Inlet: syringe; open container; stainless steel cylinder
Outlet: syringe; open container; stainless steel cylinder
Varieties of Inlet and Outlet for NanoGenizer-Quad

Troubleshooting:
Our design has minimized the occurrence of air-blocking, chamber-blocking and overload.
However, the improper operation of the homogenizer can still induce errors and cause damage to the homogenizer.

Air Blocking
Symptom: there is no pressure and no sucking from inlet
Prevention: do not run with empty inlet
Reason: there is air inside the pump
Solutions:
1) In the customer setup, press the "Degas" button.
2) Running 50mL water with 50% speed
3) Push the ball into the inlet valve with a pin

Push the ball into the inlet valve with a pin

Chamber Blocking
Symptom: overload of the pressure
Prevention: pre-treat the sample carefully; reduce the speed
Reason: there are aggregates or particles in the sample; too high a speed
Solutions:
1) Reverse flow the outlet valve with 100mL water with low speed
2) Reverse flow the chamber with water from low to high speed

Overload
Solutions:
1) Reduce the speed and close the power, wait 30 sec and restart
2) Wash with water or solvent
3) Run with clean and homo-disperse sample

No Response
Symptom: the equipment does not respond when click the “Start” button on the touch screen
Solutions:
1)Turn off the power supply and wait for 30 sec to restart
2) If there is still no response, please check the power input. The power supply of the equipment is 220V. When the external power supply is 110V, a power converter shall be used. And its INPUT port should connect to 110V while the OUTPUT port connect to 220V

Air blocking rarely causes damage to the NanoGenizer; however, the chamber blocking is harmful to the pump because of overloaded pressure in an instant.
1) Pretreat the sample carefully, and always use a clean and homo-disperse sample
2) Adjust the pressure from low to high
3) For safety, do not point the inlet or outlet of high pressure devices and equipment supplied by Genizer, including high pressure homogenizer, extruder, interaction chamber and valve, to any personnel or object that may affect safety or induce property loss.

Tips:
For facilitating the user applications, the two ports in the high pressure cylinder of the NanoGenizer are exchangeable for inlet and outlet.

Pressure and chamber selection for various applications with NanoGenizer

Cells	Mammalian cell	Insect cell	Bacteria cell	Yeast cell	Algae cell	Spore
Sample	CHO\|Hela	Sf9\|Sf21\|H5	E. Coli	Yeast	Green algae	Ganoderma
Pressure	600-800bar 8500-11500psi	600-1000bar 8500-14500psi	800-1000bar 11500-14500psi	1200-1400bar 17500-20000psi	1200-1500bar 7500-21500psi	1300-1600bar 18500-23000psi
Chamber	F20Y, F20Y-RT	F20Y, F20Y-RT	F20Y, F20Y-RT	F20Y, F12Y	F20Y, F12Y	F20Y, F12Y

Emulsions	Oil in water emulsions	Water in oil emulsions	Oil emulsion	Food	Liposome (o/w)	Liposome (w/o)
Sample	Fat emulsion	Cosmetics	Fuel	Milk	DOX	DNA\|lipopolyplex
Pressure	~20,000psi	~10,000psi	~20,000psi	~10,000psi	~20,000psi	~8,000psi
Chamber	F20Y, F12Y	F20Y	F20Y, F12Y	F20Y	F20Y, F12Y	F20Y

Dispersions	Pigments	Creams	Battery	Particle aggregation	Graphene	Nanotubes
Sample	Inks, Coatings	Creams	Lithium/Solar cell	Nano fibril	Graphene	Carbon Nanotubes
Pressure	~25,000psi	~20,000psi	~20,000psi	~25,000psi	~20,000psi	~20,000psi
Chamber	F20Y, F12Y	F20Y, F12Y	F20Y, F12Y	F20Y, F12Y	F20Y, F12Y	F20Y, F12Y

NanoGenizer-Quad (Quad Pump)

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